Major vault protein

MVP
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1Y7X
Identifiers
Aliases	MVP, LRP, VAULT1, major vault protein
External IDs	MGI: 1925638 HomoloGene: 3752 GeneCards: MVP
Gene ontology Molecular function • protein phosphatase binding • protein binding • protein kinase binding • identical protein binding Cellular component • cytoplasm • perinuclear region of cytoplasm • nuclear pore • intracellular ribonucleoprotein complex • extracellular exosome • cytoskeleton • membrane • nucleus • extracellular region • cytosol • secretory granule lumen • ficolin-1-rich granule lumen Biological process • protein transport • mRNA transport • negative regulation of protein tyrosine kinase activity • ERBB signaling pathway • negative regulation of signaling • negative regulation of protein autophosphorylation • neutrophil degranulation • transport Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	9961	78388
Ensembl	ENSG00000013364	ENSMUSG00000030681
UniProt	Q14764	Q9EQK5
RefSeq (mRNA)	NM_017458 NM_001293204 NM_001293205 NM_005115	NM_080638
RefSeq (protein)	NP_001280133 NP_001280134 NP_005106 NP_059447 NP_001280134.1	NP_542369
Location (UCSC)	Chr 16: 29.82 – 29.85 Mb	Chr 7: 126.99 – 127.01 Mb
PubMed search

1Y7X

9961

78388

ENSG00000013364

ENSMUSG00000030681

Q14764

Q9EQK5

NM_017458
NM_001293204
NM_001293205
NM_005115

NM_080638

NP_001280133
NP_001280134
NP_005106
NP_059447
NP_001280134.1

NP_542369

Major vault protein is a protein that in humans is encoded by the MVP gene. 78 copies of the protein assemble into the large compartments called vaults, illustrated and discussed in the article on Vault (organelle).

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Wikipedia