Margaret of Guelders (11 August 1436, Grave, North Brabant - 2 November 1486, Simmern) was a noblewoman from what is now the Netherlands. She was the daughter of Arnold of Egmond, Duke of Guelders, and Catherine of Cleves (1417–1479). Via her mother she was a granddaughter of Adolph I, Duke of Cleves. In Lobith on 6 August 1454 she married Frederick I, Count Palatine of Simmern - they had ten children: