Medroxyprogesterone

Medroxyprogesterone

Clinical data
Pregnancy category	X
ATC code	None
Identifiers
IUPAC name 17α-Hydroxy-6α-methylpregn-4-ene-3,20-dione
CAS Number	520-85-4
PubChem CID	1063110631
ChemSpider	10185
ECHA InfoCard	100.007.545
Chemical and physical data
Formula	C22H32O3
Molar mass	344.488 g/mol
3D model (Jmol)	Interactive image
SMILES O=C4\C=C2/[C@]([C@H]1CC[C@@]3([C@@](O)(C(=O)C)CC[C@H]3[C@@H]1C[C@@H]2C)C)(C)CC4
InChI InChI=1S/C22H32O3/c1-13-11-16-17(20(3)8-5-15(24)12-19(13)20)6-9-21(4)18(16)7-10-22(21,25)14(2)23/h12-13,16-18,25H,5-11H2,1-4H3/t13-,16+,17-,18-,20+,21-,22-/m0/s1 Key:FRQMUZJSZHZSGN-HBNHAYAOSA-N

Medroxyprogesterone (INN, BAN), also known as 17α-hydroxy-6α-methylprogesterone, and abbreviated as MP, is a steroidal progestin drug which was never marketed for use in humans. A derivative, medroxyprogesterone acetate (MPA), is used as a medication. Compared to MPA, MP is over two orders of magnitude less potent as a progestogen. As such, MP itself is not used clinically, though it has seen limited use in veterinary medicine under the trade name Controlestril in France. In addition, it is a metabolite of MPA.

While medroxyprogesterone is sometimes used as a synonym for medroxyprogesterone acetate, what is normally being administered is MPA and not MP.