Melitracen

Melitracen

Clinical data
AHFS/Drugs.com	International Drug Names
Routes of administration	Oral, IM
ATC code	N06AA14 (WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name 3-(10,10-dimethylanthracen-9(10H)-ylidene)-N,N-dimethylpropan-1-amine
CAS Number	5118-29-6 N
PubChem CID	25382
ChemSpider	23697 Y
UNII	Q7T0Y1109Z
KEGG	D08171 Y
ChEMBL	CHEMBL110094 Y
ECHA InfoCard	100.023.507
Chemical and physical data
Formula	C21H25N
Molar mass	291.43 g/mol
3D model (Jmol)	Interactive image
SMILES c3ccc2c(/C(c1c(cccc1)C2(C)C)=C/CCN(C)C)c3
InChI InChI=1S/C21H25N/c1-21(2)19-13-7-5-10-17(19)16(12-9-15-22(3)4)18-11-6-8-14-20(18)21/h5-8,10-14H,9,15H2,1-4H3 Y Key:GWWLWDURRGNSRS-UHFFFAOYSA-N Y
NY (what is this?)

Melitracen (Adaptol, Dixeran, Melixeran, Thymeol, Trausabun) is a tricyclic antidepressant (TCA) marketed in Europe and Japan by Lundbeck and Takeda, respectively, for the treatment of depression and anxiety. In addition to single drug preparations, it is also available as Deanxit, a combination product containing both melitracen and flupentixol.

The pharmacology of melitracen has not been properly investigated and is largely unknown, but it is likely to act in a similar manner to other TCAs. Indeed, melitracen is reported to have imipramine and amitriptyline-like effects and efficacy against depression and anxiety, though with improved tolerability and a somewhat faster onset of action.