| Murid herpesvirus 4 | |
|---|---|
| Virus classification | |
| Group: | Group I (dsDNA) |
| Family: | Herpesviridae |
| Subfamily: | Gammaherpesvirinae |
| Genus: | Rhadinovirus |
| Species: | Murid herpesvirus 4 (MuHV 4) |
Murid herpesvirus 4 (MuHV 4) is a virus in the genus Rhadinovirus. It is a member of the subfamily Gammaherpesvirinae in the family Herpesviridae. MuHV 4 infects mice via the nasal passages and causes an acute infectious mononucleosis-like syndrome with elevated levels of leukocytes, and shifts in the relative proportion of lymphocytes along with the appearance of atypical mononuclear cells. Murid herpesvirus 4 currently serves as a model for study of human gamma-herpesvirus pathogenesis.
Seven strains of MuHV 4 have been isolated, including the following six: