Naltriben

Naltriben

Clinical data
ATC code	none
Identifiers
CAS Number	111555-58-9
PubChem CID	5486827
IUPHAR/BPS	1640
ChemSpider	4589081 Y
ChEMBL	CHEMBL100940 Y
Chemical and physical data
Formula	C26H25NO4
Molar mass	415.480 g/mol
3D model (Jmol)	Interactive image
SMILES Oc3c2O[C@H]6c1oc8ccccc8c1C[C@@]5(O)[C@H]4N(CC[C@@]56c2c(cc3)C4)CC7CC7
InChI InChI=1S/C26H25NO4/c28-18-8-7-15-11-20-26(29)12-17-16-3-1-2-4-19(16)30-22(17)24-25(26,21(15)23(18)31-24)9-10-27(20)13-14-5-6-14/h1-4,7-8,14,20,24,28-29H,5-6,9-13H2/t20-,24+,25+,26-/m1/s1 Y Key:ZHVWWEYETMPAMX-IFKAHUTRSA-N Y

Naltriben is a potent and selective antagonist for the delta opioid receptor, which is used in scientific research. It has similar effects to the more widely used δ antagonist naltrindole, but with different binding affinity for the δ₁ and δ₂ subtypes, which makes it useful for distinguishing the subtype selectivity of drugs acting at the δ receptors. It also acts as a κ-opioid agonist at high doses.