Nicolas Le Novère
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| Born | 12 March 1969 |
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| Known for | BioModels Database, SBGN, SBML, MIRIAM |
Nicolas Le Novère is a British and French biologist, senior group leader at the Babraham Institute. His research is focused on modeling signaling pathways and developing tools to share mathematical models.
Le Novère obtained his Baccalauréat at the Prytanée National Militaire. He received a MSc (1993) in Biology and Biochemistry from the École Normale Supérieure, a BSc in Cellular Biology and Physiology (1991), and a PhD in Molecular and Cellular Pharmacology (1998) from the Pierre and Marie Curie University. From 1999 to 2001, he was a Postdoctoral Fellow at the University of Cambridge (UK).
The first part of Le Novère's career, in the laboratory of Jean-Pierre Changeux at the Pasteur Institute, was focused on studying Nicotinic acetylcholine receptors in the brain. He reconstructed their phylogeny, predicted and modeled their structure. He also investigated the role of the alpha6 subunit in the dopaminergic neurons of the mesencephalon.
During his post-doctoral fellowship in the group of Dennis Bray at the University of Cambridge, he modeled the molecular networks underlying bacterial chemotaxis. Le Novère then became involved in the development standards to share mathematical models such as SBML, of which he would later become editor.
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