North Carolina Highway 157
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| Route information | ||||
| Maintained by NCDOT | ||||
| Length: | 29.3 mi (47.2 km) | |||
| Major junctions | ||||
| South end: |
    I‑85 / US 15 / US 70 / US 501 in Durham
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 NC 57 in Caldwell
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| North end: |
 US 158 / US 501 / NC 57 in Roxboro
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| Location | ||||
| Counties: | Durham, Orange, Person | |||
| Highway system | ||||
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North Carolina Highway 157 (NC 157) is a north–south highway that travels from Interstate 85 (I-85), U.S. Routes 15 (US 15), US 70, and US 501 in Durham, to US 158/US 501 and NC 57 in Roxboro. It is called Guess Road, while it is in Durham.
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