North Dry Sac River is a stream in Greene and Polk counties in the Ozarks of southwest Missouri.
Coordinates of the source are 37°22′08″N 93°12′22″W / 37.36889°N 93.20611°W and the coordinates of the confluence with the Little Sac River are: 37°26′22″N 93°23′47″W / 37.43944°N 93.39639°W.
North Dry Sac River, a tributary of the Little Sac River, was named for its tendency to run dry.