The Nyumbani Children's Home was founded by Father Angelo D'Agostino and Sister Mary Owens in 1992 to serve mostly abandoned children created by the AIDS pandemic.
Originally a medical doctor in the US Air Force, D'Agostino joined the Jesuits early in his career, focused on psychiatry, and held various teaching positions. But it was through his experience working with multiple Jesuit charities that D'Agostino learned of the dire need for specialized facilities for abandoned children in Nairobi, Kenya. Today over 100 orphans or abandoned children live at Nyumbani Home located in Karen, Nairobi.
In 1998, the recognition that there was a need to expand the basic initiative of Nyumbani Home to other locales gave birth to the Lea Toto program. This is "a community-based outreach program providing services to HIV+ children and their families in the Kangemi, Waithaka, Kawangware, Riruta, Mutuini, Ruthimitu, Kibera and Kariobangi communities of Nairobi, Kenya." Nyumbani’s Lea Toto HIV/AIDS program operates eight centers and serves between 2,100 and 3,100 HIV-positive children and up to 15,000 family members every year.
The Nyumbani programs are supported by international boards the United States, United Kingdom, Ireland, Spain, Italy and Kenya. In addition to individual donations and corporate sponsorships, the executive boards around the world raise critical operating funds, provide expertise and much-needed volunteers.
Based on past success, a related effort called Nyumbani Village was spawned to support both orphans and elders impacted by the AIDS pandemic. Located on 1,000 acres (4.0 km2) donated by the Kitui District County Council, Nyumbani Village is conceived to support between 1280-1600 individuals via a self-sustaining agricultural based venture. Shortly after its inauguration, on 20 November 2006, Fr. D'Ag died. But with his organizational skills, this new venture also continued to prosper. In 2016 it had 120 employees tending to 100 elderly grandparents and 1000 children. In September 2016, actress Danai Gurira presented a video about the village and the work being done in Africa as part of the 2016 Global Citizen Festival in New York City. The pharmaceuticals company Johnson & Johnson is a sponsoring partner via Global Citizen, in an outreach effort to promote social action and awareness.