OBSCN

OBSCN
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1V1C, 2CR6, 2DKU, 2DM7, 2E7B, 2EDF, 2EDH, 2EDL, 2EDQ, 2EDR, 2EDT, 2EDW, 2ENY, 2EO1, 2GQH, 2YZ8, 4C4K, 2MWC, 4RSV, 2N56
Identifiers
Aliases	OBSCN, ARHGEF30, UNC89, obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
External IDs	MGI: 2681862 HomoloGene: 70869 GeneCards: OBSCN
Gene ontology Molecular function • ankyrin binding • metal ion binding • nucleotide binding • protein kinase activity • transferase activity • protein serine/threonine kinase activity • kinase activity • structural constituent of muscle • calmodulin binding • ATP binding • titin binding • protein binding • guanyl-nucleotide exchange factor activity • Rho guanyl-nucleotide exchange factor activity Cellular component • cytoplasm • myofibril • M band • Z disc • cytosol • nuclear body • nucleus • plasma membrane • membrane • sarcolemma Biological process • sarcomere organization • regulation of Rho protein signal transduction • positive regulation of GTPase activity • multicellular organism development • positive regulation of apoptotic process • protein phosphorylation • protein localization to M-band • regulation of small GTPase mediated signal transduction • cell differentiation • phosphorylation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	84033	380698
Ensembl	ENSG00000154358	ENSMUSG00000061462
UniProt	Q5VST9	A2AAJ9
RefSeq (mRNA)	NM_001098623 NM_001271223 NM_052843	NM_001003914 NM_001171512 NM_199152
RefSeq (protein)	NP_001092093 NP_001258152 NP_443075	n/a
Location (UCSC)	Chr 1: 228.21 – 228.38 Mb	Chr 11: 58.99 – 59.14 Mb
PubMed search

1V1C, 2CR6, 2DKU, 2DM7, 2E7B, 2EDF, 2EDH, 2EDL, 2EDQ, 2EDR, 2EDT, 2EDW, 2ENY, 2EO1, 2GQH, 2YZ8, 4C4K, 2MWC, 4RSV, 2N56

84033

380698

ENSG00000154358

ENSMUSG00000061462

...
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