OGG1

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1EBM, 1FN7, 1HU0, 1KO9, 1LWV, 1LWW, 1LWY, 1M3H, 1M3Q, 1N39, 1N3A, 1N3C, 1YQK, 1YQL, 1YQM, 1YQR, 2I5W, 2NOB, 2NOE, 2NOF, 2NOH, 2NOI, 2NOL, 2NOZ, 2XHI, 3IH7, 3KTU, 5AN4

Identifiers

Aliases

OGG1, HMMH, HMUTM, OGH1, 8-oxoguanine DNA glycosylase

External IDs

OMIM: 601982 MGI: 1097693 HomoloGene: 1909 GeneCards: OGG1

Gene ontology
Molecular function	• DNA binding • microtubule binding • hydrolase activity, acting on glycosyl bonds • oxidized purine DNA binding • catalytic activity • protein binding • oxidized purine nucleobase lesion DNA N-glycosylase activity • lyase activity • DNA-(apurinic or apyrimidinic site) lyase activity • endonuclease activity • 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity • hydrolase activity • damaged DNA binding • DNA N-glycosylase activity
Cellular component	• protein complex • mitochondrion • nuclear matrix • nucleus • nuclear speck • nucleoplasm
Biological process	• depurination • nucleotide-excision repair • response to estradiol • regulation of transcription, DNA-templated • response to light stimulus • aging • negative regulation of apoptotic process • cellular response to cadmium ion • regulation of protein import into nucleus, translocation • response to oxidative stress • depyrimidination • acute inflammatory response • response to radiation • response to folic acid • metabolic process • response to ethanol • nucleotide-excision repair, DNA incision • negative regulation of double-strand break repair via single-strand annealing • response to drug • base-excision repair • cellular response to DNA damage stimulus • DNA repair
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


4968


18294

Ensembl


ENSG00000114026


ENSMUSG00000030271

UniProt


O15527


O08760

RefSeq (mRNA)

NM_002542 NM_016819 NM_016820 NM_016821 NM_016826
NM_016827 NM_016828 NM_016829


NM_010957

RefSeq (protein)

NP_002533 NP_058212 NP_058213 NP_058214 NP_058434
NP_058436 NP_058437 NP_058438 NP_058436.1 NP_058434.1


NP_035087

Location (UCSC)

Chr 3: 9.75 – 9.79 Mb

Chr 6: 113.33 – 113.34 Mb

PubMed search

8-oxoguanine DNA glycosylase, N-terminal domain

structure of catalytically inactive q315a human 8-oxoguanine glycosylase complexed to 8-oxoguanine dna

Identifiers

Symbol

OGG_N

Pfam clan

Available protein structures:
Pfam	structures
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

Available protein structures:
Pfam	structures
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

1EBM, 1FN7, 1HU0, 1KO9, 1LWV, 1LWW, 1LWY, 1M3H, 1M3Q, 1N39, 1N3A, 1N3C, 1YQK, 1YQL, 1YQM, 1YQR, 2I5W, 2NOB, 2NOE, 2NOF, 2NOH, 2NOI, 2NOL, 2NOZ, 2XHI, 3IH7, 3KTU, 5AN4

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