OSMR

OSMR
Identifiers
Aliases	OSMR, OSMRB, PLCA1, IL-31R-beta, IL-31RB, oncostatin M receptor
External IDs	OMIM: 601743 MGI: 1330819 HomoloGene: 2972 GeneCards: OSMR
Gene ontology Molecular function • cytokine receptor activity • oncostatin-M receptor activity • growth factor binding Cellular component • integral component of membrane • oncostatin-M receptor complex • plasma membrane • apical plasma membrane • membrane Biological process • positive regulation of acute inflammatory response • response to cytokine • oncostatin-M-mediated signaling pathway • positive regulation of cell proliferation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	9180	18414
Ensembl	ENSG00000145623	ENSMUSG00000022146
UniProt	Q99650	O70458
RefSeq (mRNA)	NM_001168355 NM_003999 NM_001323504 NM_001323505 NM_001323506 NM_001323507	NM_011019 NM_001310469
RefSeq (protein)	NP_001161827 NP_001310433 NP_001310434 NP_001310435 NP_001310436 NP_003990	NP_001297398.1 NP_035149.2 NP_001297398 NP_035149
Location (UCSC)	Chr 5: 38.85 – 38.95 Mb	Chr 15: 6.81 – 6.87 Mb
PubMed search

9180

18414

ENSG00000145623

ENSMUSG00000022146

Q99650

O70458

NM_001323507

NM_011019
NM_001310469

NP_003990

NP_001297398.1
NP_035149.2
NP_001297398
NP_035149

Oncostatin-M specific receptor subunit beta also known as the oncostatin M receptor, is one of the receptor proteins for oncostatin M, that in humans is encoded by the OSMR gene.

OSMR is a member of the type I cytokine receptor family. This protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events.

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