PF-592,379

PF-592,379

Clinical data
Routes of administration	Oral
Legal status
Legal status	Investigational (discontinued)
Identifiers
IUPAC name 5-[(2R,5S)-5-methyl-4-propylmorpholin-2-yl]pyridin-2-amine
PubChem CID	10263487
IUPHAR/BPS	7683
ChemSpider	8438966
Chemical and physical data
Formula	C13H21N3O
Molar mass	235.33 g/mol
3D model (Jmol)	Interactive image
SMILES CCCN([C@@H](C)CO1)C[C@H]1C2=CN=C(N)C=C2
InChI InChI=1S/C13H21N3O/c1-3-6-16-8-12(17-9-10(16)2)11-4-5-13(14)15-7-11/h4-5,7,10,12H,3,6,8-9H2,1-2H3,(H2,14,15)/t10-,12-/m0/s1 Key:DFTCYTDJDXZFSK-JQWIXIFHSA-N

PF-592,379 is a drug developed by Pfizer which acts as a potent, selective and orally active agonist for the dopamine D₃ receptor, which is under development as a potential medication for the treatment of female sexual dysfunction and male erectile dysfunction. Unlike some other less selective D₃ agonists, PF-592,379 showed no evidence of abuse potential in animal studies, and so was selected for further development and potentially human clinical trials.Development has since been discontinued.