PGRMC1

PGRMC1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4X8Y
Identifiers
Aliases	PGRMC1, HPR6.6, MPR, progesterone receptor membrane component 1
External IDs	MGI: 1858305 HomoloGene: 48457 GeneCards: PGRMC1
Gene ontology Molecular function • steroid binding • protein binding • heme binding • lipid binding Cellular component • organelle membrane • integral component of membrane • extracellular exosome • endoplasmic reticulum membrane • endomembrane system • membrane • intracellular membrane-bounded organelle • endoplasmic reticulum • plasma membrane • specific granule membrane Biological process • neutrophil degranulation Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	10857	53328
Ensembl	ENSG00000101856	ENSMUSG00000006373
UniProt	O00264 Q6IB11	O55022
RefSeq (mRNA)	NM_006667 NM_001282621	NM_016783
RefSeq (protein)	NP_001269550 NP_006658 NP_006658.1	NP_058063.2 NP_058063
Location (UCSC)	Chr X: 119.24 – 119.24 Mb	Chr X: 36.6 – 36.61 Mb
PubMed search

4X8Y

10857

53328

ENSG00000101856

ENSMUSG00000006373

O00264
Q6IB11

O55022

NM_006667
NM_001282621

NM_016783

NP_001269550
NP_006658
NP_006658.1

NP_058063.2
NP_058063

Progesterone receptor membrane component 1 (abbreviated PGRMC1) is a protein which co-purifies with progesterone binding proteins in the liver and ovary. In humans, the PGRMC1 protein is encoded by the PGRMC1 gene. The Sigma-2 receptor was recently identified as a protein that binds the PGRMC1 protein.

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Wikipedia