POLDIP3

POLDIP3
Identifiers
Aliases	POLDIP3, PDIP46, SKAR, polymerase (DNA) delta interacting protein 3
External IDs	MGI: 1921076 HomoloGene: 13007 GeneCards: POLDIP3
Gene ontology Molecular function • protein binding • nucleic acid binding • RNA binding Cellular component • exon-exon junction complex • transcription export complex • nucleus • nuclear speck • cytoplasm • cytosol • P-body • nucleoplasm Biological process • transport • poly(A)+ mRNA export from nucleus • mRNA transport • regulation of translation • positive regulation of translation • termination of RNA polymerase II transcription • mRNA export from nucleus • mRNA 3'-end processing • RNA export from nucleus Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	84271	73826
Ensembl	ENSG00000100227	ENSMUSG00000041815
UniProt	Q9BY77 Q8WUT1	Q8BG81
RefSeq (mRNA)	NM_001278657 NM_032311 NM_178136	NM_178627 NM_001347082
RefSeq (protein)	NP_001265586 NP_115687 NP_835237	NP_848742.1 NP_001334011 NP_848742
Location (UCSC)	Chr 22: 42.58 – 42.61 Mb	Chr 15: 83.13 – 83.15 Mb
PubMed search

84271

73826

ENSG00000100227

ENSMUSG00000041815

Q9BY77
Q8WUT1

Q8BG81

NM_001278657
NM_032311
NM_178136

NM_178627
NM_001347082

NP_001265586
NP_115687
NP_835237

NP_848742.1
NP_001334011
NP_848742

Polymerase delta-interacting protein 3 is an enzyme that in humans is encoded by the POLDIP3 gene.

This gene encodes a protein that interacts with the DNA polymerase delta p50 subunit. This protein is a specific target of S6 kinase 1 and regulates cell growth. Two transcript variants that encode different protein isoforms have been identified.

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