POLE2

POLE2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2V6Z
Identifiers
Aliases	POLE2, DPE2, polymerase (DNA) epsilon 2, accessory subunit, DNA polymerase epsilon 2, accessory subunit
External IDs	MGI: 1197514 HomoloGene: 2015 GeneCards: POLE2
Gene ontology Molecular function • transferase activity • DNA binding • nucleotidyltransferase activity • protein binding • DNA-directed DNA polymerase activity Cellular component • intracellular membrane-bounded organelle • nucleus • nucleoplasm • nuclear body • epsilon DNA polymerase complex Biological process • G1/S transition of mitotic cell cycle • DNA replication initiation • DNA repair • error-prone translesion synthesis • DNA replication • DNA-dependent DNA replication • telomere maintenance via semi-conservative replication Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	5427	18974
Ensembl	ENSG00000100479	ENSMUSG00000020974
UniProt	P56282	O54956
RefSeq (mRNA)	NM_001197330 NM_001197331 NM_002692 NM_001348384 NM_001348385	NM_011133
RefSeq (protein)	NP_001184259 NP_001184260 NP_002683 NP_001335313 NP_001335314	NP_035263
Location (UCSC)	Chr 14: 49.64 – 49.69 Mb	Chr 12: 69.2 – 69.23 Mb
PubMed search

2V6Z

5427

18974

ENSG00000100479

ENSMUSG00000020974

P56282

O54956

NM_001197330
NM_001197331
NM_002692
NM_001348384
NM_001348385

NM_011133

NP_001184259
NP_001184260
NP_002683
NP_001335313
NP_001335314

NP_035263

DNA polymerase epsilon subunit 2 is an enzyme that in humans is encoded by the POLE2 gene.

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Wikipedia