PPP1CA

PPP1CA

Protein PPP1CA PDB 1fjm.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
3E7A, 3E7B, 3EGG, 3EGH, 3HVQ, 3N5U, 3V4Y, 4G9J, 4MOV, 4MOY, 4MP0, 4XPN, 1FJM

Identifiers

PPP1CA, PP-1A, PP1A, PP1alpha, PPP1A, protein phosphatase 1 catalytic subunit alpha

External IDs

MGI: 103016 HomoloGene: 105262 GeneCards: PPP1CA

Gene ontology
Molecular function	• phosphoprotein phosphatase activity • phosphatase activity • protein complex binding • protein serine/threonine phosphatase activity • metal ion binding • protein phosphatase 1 binding • protein binding • ribonucleoprotein complex binding • hydrolase activity • cadherin binding involved in cell-cell adhesion
Cellular component	• cytoplasm • perikaryon • plasma membrane • dendritic spine • nucleoplasm • neuronal cell body • protein phosphatase type 1 complex • glycogen granule • PTW/PP1 phosphatase complex • nucleolus • neuron projection • extracellular exosome • nucleus • nuclear chromosome, telomeric region • cytosol • cell-cell adherens junction
Biological process	• carbohydrate metabolic process • lung development • regulation of canonical Wnt signaling pathway • protein dephosphorylation • negative regulation of protein binding • circadian regulation of gene expression • cell division • positive regulation of extrinsic apoptotic signaling pathway in absence of ligand • regulation of circadian rhythm • glycogen metabolic process • regulation of glycogen biosynthetic process • cell cycle • regulation of translational initiation by eIF2 alpha dephosphorylation • beta-catenin destruction complex disassembly • branching morphogenesis of an epithelial tube • entrainment of circadian clock by photoperiod • regulation of glycogen catabolic process • dephosphorylation • cell-cell adhesion
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE PPP1CA 200846 s at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


5499


19045


ENSG00000172531


n/a


P62136


P62137

RefSeq (mRNA)


NM_206873 NM_001008709 NM_002708


NM_031868

RefSeq (protein)


NP_001008709 NP_002699 NP_996756


NP_114074.1 NP_114074

Location (UCSC)

Chr 11: 67.4 – 67.42 Mb

Chr 19: 4.19 – 4.2 Mb

PubMed search

3E7A, 3E7B, 3EGG, 3EGH, 3HVQ, 3N5U, 3V4Y, 4G9J, 4MOV, 4MOY, 4MP0, 4XPN, 1FJM

ENSG00000172531

n/a

NM_206873
NM_001008709
NM_002708

NP_001008709
NP_002699
NP_996756

...
Wikipedia

...