PRKCQ

PRKCQ
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1XJD, 2ENJ, 2ENN, 2ENZ, 2JED, 4Q9Z, 4RA5, 5F9E
Identifiers
Aliases	PRKCQ, PRKCT, nPKC-theta, protein kinase C theta
External IDs	MGI: 97601 HomoloGene: 21263 GeneCards: PRKCQ
Gene ontology Molecular function • transferase activity • nucleotide binding • protein kinase C activity • metal ion binding • kinase activity • protein binding • ATP binding • protein serine/threonine kinase activity • protein kinase activity Cellular component • cytoplasm • cytosol • membrane • plasma membrane • intracellular • immunological synapse • microtubule organizing center • aggresome Biological process • intracellular signal transduction • regulation of transcription, DNA-templated • positive regulation of telomere capping • phosphorylation • immune system process • positive regulation of telomere maintenance via telomerase • positive regulation of T-helper 2 cell activation • positive regulation of interleukin-4 production • positive regulation of interleukin-2 biosynthetic process • axon guidance • platelet activation • Fc-epsilon receptor signaling pathway • protein phosphorylation • negative regulation of T cell apoptotic process • negative regulation of insulin receptor signaling pathway • positive regulation of T cell activation • membrane protein ectodomain proteolysis • positive regulation of NF-kappaB transcription factor activity • peptidyl-serine phosphorylation • positive regulation of T-helper 17 type immune response • regulation of cell growth • positive regulation of T cell proliferation • positive regulation of telomerase activity • cell chemotaxis • positive regulation of interleukin-17 production • inflammatory response • T cell receptor signaling pathway • regulation of platelet aggregation • execution phase of apoptosis Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	5588	18761
Ensembl	ENSG00000065675	ENSMUSG00000026778
UniProt	Q04759	Q02111
RefSeq (mRNA)	NM_001242413 NM_001282644 NM_001282645 NM_006257 NM_001323265 NM_001323266 NM_001323267	NM_008859
RefSeq (protein)	NP_001229342 NP_001269573 NP_001269574 NP_001310194 NP_001310195 NP_001310196 NP_006248	NP_032885.1 NP_032885
Location (UCSC)	Chr 10: 6.43 – 6.58 Mb	Chr 2: 11.17 – 11.3 Mb
PubMed search

1XJD, 2ENJ, 2ENN, 2ENZ, 2JED, 4Q9Z, 4RA5, 5F9E

5588

18761

ENSG00000065675

ENSMUSG00000026778

Q04759

Q02111

NM_001323266
NM_001323267

NM_008859

NP_001310196
NP_006248

NP_032885.1
NP_032885

Protein kinase C theta (PKC-θ) is an enzyme that in humans is encoded by the PRKCQ gene.

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Wikipedia