PRKD2

PRKD2

Protein PRKD2 PDB 2coa.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2COA, 3BGM, 4NNX, 4NNY

Identifiers

PRKD2, PKD2, nPKC-D2, HSPC187, protein kinase D2

External IDs

MGI: 2141917 HomoloGene: 9516 GeneCards: PRKD2

Gene ontology
Molecular function	• transferase activity • protein kinase activity • nucleotide binding • protein kinase C activity • metal ion binding • kinase activity • protein binding • ATP binding • protein serine/threonine kinase activity
Cellular component	• cytoplasm • Golgi apparatus • membrane • nucleoplasm • nucleus • cytosol • plasma membrane • intracellular
Biological process	• positive regulation of vascular endothelial growth factor receptor signaling pathway • GO:0007242 intracellular signal transduction • positive regulation of endothelial cell proliferation • adaptive immune response • phosphorylation • immune system process • endothelial tube morphogenesis • positive regulation of fibroblast growth factor receptor signaling pathway • positive regulation of T cell receptor signaling pathway • positive regulation of endothelial cell chemotaxis • positive regulation of sequence-specific DNA binding transcription factor activity • cell death • protein kinase D signaling • positive regulation of intracellular signal transduction • positive regulation of peptidyl-serine phosphorylation • positive regulation of angiogenesis • positive regulation of endothelial cell migration • protein phosphorylation • positive regulation of histone deacetylase activity • positive regulation of CREB transcription factor activity • vascular endothelial growth factor receptor signaling pathway • cell adhesion • positive regulation of NF-kappaB transcription factor activity • positive regulation of interleukin-2 production • peptidyl-serine phosphorylation • angiogenesis • positive regulation of interleukin-8 production • positive regulation of blood vessel endothelial cell migration • positive regulation of DNA biosynthetic process • positive regulation of ERK1 and ERK2 cascade • positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway • protein autophosphorylation • cellular response to vascular endothelial growth factor stimulus • T cell receptor signaling pathway • positive regulation of transcription from RNA polymerase II promoter • positive regulation of cell adhesion • sphingolipid biosynthetic process
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE PRKD2 209282 at fs.png

PBB GE PRKD2 38269 at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


25865


101540


ENSG00000105287


ENSMUSG00000041187


Q9BZL6


Q8BZ03

RefSeq (mRNA)


NM_001079880 NM_001079881 NM_001079882 NM_016457


NM_001252458 NM_178900

RefSeq (protein)


NP_001073349 NP_001073350 NP_001073351 NP_057541


NP_001239387.1 NP_849231.1 NP_001239387 NP_849231

Location (UCSC)

Chr 19: 46.67 – 46.72 Mb

Chr 7: 16.84 – 16.87 Mb

PubMed search

2COA, 3BGM, 4NNX, 4NNY

ENSG00000105287

ENSMUSG00000041187

NM_001079880
NM_001079881
NM_001079882
NM_016457

NM_001252458
NM_178900

NP_001073349
NP_001073350
NP_001073351
NP_057541

NP_001239387.1
NP_849231.1
NP_001239387
NP_849231

...
Wikipedia

...