PTGES3

PTGES3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1EJF
Identifiers
Aliases	PTGES3, P23, TEBP, cPGES, prostaglandin E synthase 3
External IDs	MGI: 1929282 HomoloGene: 128197 GeneCards: PTGES3
Gene ontology Molecular function • unfolded protein binding • telomerase activity • isomerase activity • protein binding • prostaglandin-E synthase activity • Hsp90 protein binding • DNA polymerase binding Cellular component • nucleoplasm • chromosome, telomeric region • telomerase holoenzyme complex • extracellular exosome • nucleus • cytoplasm • cytosol • protein complex Biological process • prostaglandin metabolic process • lipid metabolic process • cyclooxygenase pathway • fatty acid metabolic process • fatty acid biosynthetic process • regulation of cellular response to heat • prostaglandin biosynthetic process • chaperone cofactor-dependent protein refolding • telomere maintenance • signal transduction • xenobiotic metabolic process • telomere maintenance via telomerase • positive regulation of phosphorylation • positive regulation of telomerase activity • telomerase holoenzyme complex assembly • protein stabilization • chaperone-mediated protein complex assembly Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	10728	56351
Ensembl	ENSG00000110958	ENSMUSG00000071072
UniProt	Q15185	Q9R0Q7
RefSeq (mRNA)	NM_001282601 NM_001282602 NM_001282603 NM_001282604 NM_001282605 NM_006601	NM_019766
RefSeq (protein)	NP_001269530 NP_001269531 NP_001269532 NP_001269533 NP_001269534 NP_006592	NP_062740
Location (UCSC)	Chr 12: 56.66 – 56.69 Mb	Chr 10: 128.06 – 128.08 Mb
PubMed search

1EJF

10728

56351

ENSG00000110958

ENSMUSG00000071072

Q15185

Q9R0Q7

NM_006601

NM_019766

NP_006592

NP_062740

Prostaglandin E synthase 3 (cytosolic) is an enzyme that in humans is encoded by the PTGES3 gene.

The protein encoded by this gene is also known as p23 which functions as a chaperone which is required for proper functioning of the glucocorticoid and other steroid receptors.

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Wikipedia