PTPRS

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2FH7, 2YD2, 2YD3, 2YD9, 4BPC, 4PBX

Identifiers

Aliases

PTPRS, PTPSIGMA, protein tyrosine phosphatase, receptor type S, R-PTP-S, R-PTP-sigma

External IDs

MGI: 97815 HomoloGene: 20626 GeneCards: PTPRS

Gene ontology
Molecular function	• phosphatase activity • protein binding • hydrolase activity • phosphoprotein phosphatase activity • protein tyrosine phosphatase activity • heparin binding • chondroitin sulfate binding • heparan sulfate proteoglycan binding
Cellular component	• integral component of membrane • integral component of plasma membrane • extracellular exosome • membrane • plasma membrane • integral component of synaptic vesicle membrane • integral component of postsynaptic density membrane • postsynaptic density of dendrite • cell junction • axon • synaptic vesicle membrane • cytoplasmic vesicle • cell projection • neuron projection • perikaryon • synapse • postsynaptic membrane
Biological process	• cell adhesion • dephosphorylation • protein dephosphorylation • negative regulation of interferon-alpha production • negative regulation of interferon-beta production • negative regulation of toll-like receptor 9 signaling pathway • negative regulation of neuron projection development • spinal cord development • cerebellum development • hippocampus development • cerebral cortex development • corpus callosum development • negative regulation of axon extension • peptidyl-tyrosine dephosphorylation • negative regulation of collateral sprouting • negative regulation of axon regeneration • negative regulation of dendritic spine development • establishment of endothelial intestinal barrier
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


5802


19280

Ensembl


ENSG00000105426


ENSMUSG00000013236

UniProt


Q13332


B0V2N1

RefSeq (mRNA)


NM_002850 NM_130853 NM_130854 NM_130855


NM_001252453 NM_001252455 NM_001252456 NM_011218

RefSeq (protein)


NP_002841 NP_570923 NP_570924 NP_570925


NP_001239382 NP_001239384 NP_001239385 NP_035348

Location (UCSC)

Chr 19: 5.16 – 5.34 Mb

Chr 17: 56.41 – 56.48 Mb

PubMed search

2FH7, 2YD2, 2YD3, 2YD9, 4BPC, 4PBX

NM_002850
NM_130853
NM_130854
NM_130855

NM_001252453
NM_001252455
NM_001252456
NM_011218

NP_002841
NP_570923
NP_570924
NP_570925

...
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