Phazyme
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| Clinical data | |
|---|---|
| Synonyms | simethicone (USAN US) |
| AHFS/Drugs.com | Monograph |
| Pregnancy category |
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| Routes of administration |
Oral |
| ATC code | |
| Legal status | |
| Legal status |
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| Pharmacokinetic data | |
| Bioavailability | None |
| Protein binding | 0% |
| Metabolism | Not metabolized |
| Biological half-life | N/A |
| Excretion | feces |
| Identifiers | |
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| CAS Number | |
| PubChem CID | |
| ChemSpider |
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| ChEMBL | |
| ECHA InfoCard | 100.107.016 |
| Chemical and physical data | |
| Formula | (C2H6OSi)n · (SiO2)m |
| Molar mass | variable |
  (what is this?)
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Simeticone is an anti-foaming agent used to reduce bloating, discomfort or pain caused by excessive gas.
Simeticone is used to relieve the symptoms of excessive gas in the gastrointestinal tract, namely bloating, burping, and flatulence. There is not good evidence that simeticone is effective for this use.
There is no evidence that simeticone is useful to treat colic in babies.
There are no known side effects of simeticone.
Simeticone is an anti-foaming agent that decreases the surface tension of gas bubbles, causing them to combine into larger bubbles in the digestive tract. Simeticone does not reduce or prevent the formation of gas.
The chemical name for simeticone is α-(trimethylsilyl)-ω-methylpoly[oxy(dimethylsilylene)], mixture with silicon dioxide.
The INN name is "simeticone", which was added to the INN recommended list in 1999.
Simeticone is marketed under many brand names and in many combination drugs; it is also marketed as a veterinary drug.
Brand names include A.F., Acid Off, Aero Red, Aero-OM, Aero-Sim, Aerocol, Aerox, Aesim, Aflat, Air-X, Anaflat, Antiflat, Baby Rest, Bicarsim, Bicarsim Forte, Blow-X, Bobotic, Bobotik, Carbogasol, Colic E, Colin, Cuplaton, Degas, Dentinox, Dermatix, Digesta, Dimetikon Meda, Disflatyl, Disolgas, Elugan N, Elzym, Endo-Paractol, Enterosilicona, Espaven Antigas, Espumisan, Espumisan L, Flacol, Flapex, Flatidyl, Flatoril, Flatulex, Flucolic, Gas X, Gas-X, Gaselab, Gaseoflat, Gaseoflatex, Gaseophar, Gaseoplus, Gaseovet, Gaservol, Gasnil, Gasofilm, Gastrex, Gastrosen, Gazim X, Gazix, Geludrox-HS, Genasyme, Ilio-Funkton, Imogas, Imogaze, Imonogas, Infacalm, Infacol, Infacolic, Lefax, Lefaxin, Lefoam, Logastin, Luftal, Maxi Flat, Meteosim, Metiorisan, Metsil, Mylanta, Mylicon, Mylicongas, Mylom, Mymus, Nanog, Neodrop, Neogasol, Neolanta, Orocure, Ovol, Pedicon, Phazin, Phazyme, Restime, Rugby Gas Relief, Sab Simplex, Salinal, Semecon, Semeth, Sicongast, Siflat, Silbione, Siligas, Silipin, Sim, Simcone, Simecon, Simecrin, Simedill, Simegut, Simet, Simethicon, Simethicone, Simetic, Simeticon, Simeticona, Simeticone, Siméticone, Simeticonum, Simetigast, Simflat, Simicol, Simicon, Wilcon, Wind-eze, and WindSetlers.
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