Phenylalanine hydroxylase

PAH
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1DMW, 1J8T, 1J8U, 1KW0, 1LRM, 1MMK, 1MMT, 1TDW, 1TG2, 2PAH, 3PAH, 4ANP, 5PAH, 6PAH, 5FII
Identifiers
Aliases	PAH, PH, PKU, PKU1, phenylalanine hydroxylase
External IDs	OMIM: 612349 MGI: 97473 HomoloGene: 234 GeneCards: PAH
Targeted by Drug
fenclonine
Gene ontology Molecular function • iron ion binding • amino acid binding • phenylalanine 4-monooxygenase activity • metal ion binding • monooxygenase activity • catalytic activity • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen • oxidoreductase activity Cellular component • cytosol • extracellular exosome Biological process • catecholamine biosynthetic process • neurotransmitter biosynthetic process • L-phenylalanine catabolic process • cellular amino acid biosynthetic process • aromatic amino acid family metabolic process • metabolic process • oxidation-reduction process Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	5053	18478
Ensembl	ENSG00000171759	ENSMUSG00000020051
UniProt	P00439	P16331
RefSeq (mRNA)	NM_000277	NM_008777
RefSeq (protein)	NP_000268	NP_032803.2 NP_032803
Location (UCSC)	Chr 12: 102.84 – 102.96 Mb	Chr 10: 87.52 – 87.58 Mb
PubMed search

1DMW, 1J8T, 1J8U, 1KW0, 1LRM, 1MMK, 1MMT, 1TDW, 1TG2, 2PAH, 3PAH, 4ANP, 5PAH, 6PAH, 5FII

5053

18478

ENSG00000171759

ENSMUSG00000020051

P00439

P16331

NM_000277

NM_008777

...
Wikipedia