Princess Karoline Mathilde of Schleswig-Holstein-Sonderburg-Glücksburg (Viktoria-Irene Adelheid Auguste Alberta Feodora Karoline Mathilde of Schleswig-Holstein-Sonderburg-Glücksburg; 11 May 1894 – 28 January 1972) was a member of the House of Schleswig-Holstein-Sonderburg-Glücksburg and Princess of Schleswig-Holstein-Sonderburg-Glücksburg by birth and a member of the House of Solms Baruth and Countess of Solms Baruth through her marriage to Count Hans of Solms-Baruth.

Princess Karoline Mathilde was born on 11 May 1894 at Grünholz Manor, Schleswig-Holstein, Prussia, the sixth child of Frederick Ferdinand, Duke of Schleswig-Holstein-Sonderbug-Glücksburg and his wife Princess Karoline Mathilde of Schleswig-Holstein-Sonderburg-Augustenburg.

Frederick Ferdinand was the eldest son of Friedrich, Duke of Schleswig-Holstein-Sonderburg-Glücksburg and a nephew of Christian IX of Denmark. Upon the death of his father in 1885, he had succeeded to the headship of the House of Schleswig-Holstein-Sonderburg-Glücksburg and the title of duke. Her eldest sister, Victoria Adelaide was the consort of Charles Edward, Duke of Saxe-Coburg and Gotha.

She married Count Hans of Solms-Baruth on 27 May 1920 at Glücksburg Castle. Count Hans was the third son of Friedrich II, Prince of Solms-Baruth and his wife Countess Luise of Hochberg and a younger brother of Hereditary Prince Friedrich of Solms Baruth, the husband of Karoline Mathilde's elder sister Adelaide. Solms-Baruth was one of the many minor states of the Holy Roman Empire, located in Lower Lusatia. It had lost its independence in the German Mediatization of 1806.

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