Proteolipid protein 1

PLP1

Protein PLP1 PDB 2XPG.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2XPG

Identifiers

PLP1, GPM6C, HLD1, MMPL, PLP, PLP/DM20, PMD, SPG2, proteolipid protein 1

External IDs

OMIM: 300401 MGI: 97623 HomoloGene: 448 GeneCards: PLP1

Gene location (Human)

Chr.	X chromosome (human)

Band	Xq22.2	Start	103,773,718 bp
Band	Xq22.2	End	103,792,619 bp

Gene location (Mouse)

Chr.	X chromosome (mouse)

Band	X F1\|X 59.1 cM	Start	136,822,671 bp
Band	X F1\|X 59.1 cM	End	136,839,733 bp

RNA expression pattern

More reference expression data

Gene ontology
Molecular function	• protein binding • structural constituent of myelin sheath • structural molecule activity • identical protein binding
Cellular component	• integral component of membrane • myelin sheath • plasma membrane • membrane
Biological process	• axon ensheathment • integrin-mediated signaling pathway • astrocyte development • myelination • axon development • positive regulation of gene expression • inflammatory response • glial cell differentiation • cell maturation • long-chain fatty acid biosynthetic process • substantia nigra development • central nervous system myelination • chemical synaptic transmission
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


5354


18823


ENSG00000123560


ENSMUSG00000031425


P60201


P60202

RefSeq (mRNA)


NM_199478 NM_000533 NM_001128834 NM_001305004


NM_011123 NM_001290561 NM_001290562

RefSeq (protein)


NP_000524 NP_001122306 NP_001291933 NP_955772


NP_001277490 NP_001277491 NP_035253

Location (UCSC)

Chr X: 103.77 – 103.79 Mb

Chr X: 136.82 – 136.84 Mb

PubMed search

ENSG00000123560

ENSMUSG00000031425

NM_199478
NM_000533
NM_001128834
NM_001305004

NM_011123
NM_001290561
NM_001290562

NP_000524
NP_001122306
NP_001291933
NP_955772

NP_001277490
NP_001277491
NP_035253

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Wikipedia

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