| Route 143 | ||||
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| Route information | ||||
| Maintained by Transports Québec | ||||
| Length: | 165.8 km (103.0 mi) | |||
| Major junctions | ||||
| South end: |
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Stanstead-Est |
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| North end: |
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| Location | ||||
| Counties: | Memphrémagog / Coaticook / Sherbrooke / Le Val-Saint-François / Drummond / Nicolet-Yamaska | |||
| Highway system | ||||
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Route 143 is a north/south highway on the south shore of the Saint Lawrence River. Until the mid-1970s when the province decided to renumber all highways other than autoroutes, it was known as Route/Highway 5. Its northern terminus is in Saint-François-du-Lac, at the junction of Route 132, and the southern terminus is in Stanstead at the border with Vermont where the road continues past the Derby Line-Stanstead Border Crossing as U.S. Route 5 through Derby Line to New Haven, Connecticut.
Since Autoroute 55 closely parallels Route 143 for most of its length, much commercial traffic chooses the former. However, it is a very busy route and takes much traffic from the border to the Sherbrooke local area. Route 143 closely follows the Saint-François River between Sherbrooke and Ulverton.
The road is often in notoriously poor condition, since its original cement was laid directly on a gravel road in the mid-1920s. It has been extensively resurfaced to the point the pavement is now more than three feet thick in places. Nonetheless, it heaves extensively each spring thaw.