| Route 142 | ||||
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| Maintained by MoDOT | ||||
| Length: | 130 mi (210 km) | |||
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Route 142 is a highway in southern Missouri. Its eastern terminus is at Route 53 in southern Poplar Bluff; its western terminus is at Route 101 in Bakersfield. Route 142 is the southernmost (east–west) highway in the south-central part of the state. Despite its length, there are relatively few towns on the route.