| Ruffin, South Carolina | |
|---|---|
| Unincorporated community | |
| Coordinates: 33°00′17″N 80°48′56″W / 33.00472°N 80.81556°WCoordinates: 33°00′17″N 80°48′56″W / 33.00472°N 80.81556°W | |
| Country | United States |
| State | South Carolina |
| County | Colleton |
| Elevation | 72 ft (22 m) |
| Time zone | Eastern (EST) (UTC-5) |
| • Summer (DST) | EDT (UTC-4) |
| ZIP code | 29475 |
| Area code(s) | 843 |
| GNIS feature ID | 1231754 |
Ruffin is an unincorporated community in Colleton County, South Carolina, United States. The community is located on U.S. Route 21 11 miles (18 km) northwest of Walterboro. Ruffin has a post office with ZIP code 29475, which opened on October 19, 1893.