SB-206553

SB-206553

Identifiers
IUPAC name 5-methyl-1-(3-pyridylcarbamoyl)-1,2,3,5-tetrahydropyrrolo[2,3-f]indole
CAS Number	158942-04-2
PubChem CID	516
IUPHAR/BPS	189
ChemSpider	4979
Chemical and physical data
Formula	C17H16N4O
Molar mass	292.334 g/mol
3D model (Jmol)	Interactive image
SMILES Cn2ccc(c2c3)cc1c3CCN1C(=O)Nc4cccnc4
InChI InChI=1S/C17H16N4O/c1-20-7-4-12-10-16-13(9-15(12)20)5-8-21(16)17(22)19-14-3-2-6-18-11-14/h2-4,6-7,9-11H,5,8H2,1H3,(H,19,22) Key:QJQORSLQNXDVGE-UHFFFAOYSA-N

SB-206553 is a drug which acts as a mixed antagonist for the 5-HT_2B and 5-HT_2C serotonin receptors. It has anxiolytic properties in animal studies and interacts with a range of other drugs. It has also been shown to act as a positive allosteric modulator of α₇nicotinic acetylcholine receptors.