SEMA4G

SEMA4G
Identifiers
Aliases	SEMA4G, semaphorin 4G
External IDs	MGI: 1347047 HomoloGene: 22682 GeneCards: SEMA4G
Gene ontology Molecular function • protein binding • neuropilin binding Cellular component • integral component of membrane • plasma membrane • membrane • extracellular space Biological process • multicellular organism development • cell differentiation • nervous system development • negative chemotaxis Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	57715	26456
Ensembl	ENSG00000095539	ENSMUSG00000025207
UniProt	Q9NTN9	Q9WUH7
RefSeq (mRNA)	NM_001203244 NM_017893	NM_011976
RefSeq (protein)	NP_001190173 NP_060363	NP_036106.1 NP_036106
Location (UCSC)	Chr 10: 100.97 – 100.99 Mb	Chr 19: 44.99 – 45 Mb
PubMed search

57715

26456

ENSG00000095539

ENSMUSG00000025207

Q9NTN9

Q9WUH7

NM_001203244
NM_017893

NM_011976

NP_001190173
NP_060363

NP_036106.1
NP_036106

Semaphorin-4G is a protein that in humans is encoded by the SEMA4G gene.

Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. This gene encodes a class 4 semaphorin. This gene and the gene for mitochondrial ribosomal protein L43 overlap at map location 10q24.31 and are transcribed in opposite directions.

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Wikipedia