SF3B14

SF3B6
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2F9D, 2F9J, 2FHO, 3LQV
Identifiers
Aliases	SF3B6, HSPC175, Ht006, P14, SAP14, SAP14a, SF3B14, SF3B14a, CGI-110, splicing factor 3b subunit 6
External IDs	MGI: 1913305 HomoloGene: 9360 GeneCards: SF3B6
Gene ontology Molecular function • nucleic acid binding • RNA binding Cellular component • catalytic step 2 spliceosome • U12-type spliceosomal complex • U2-type spliceosomal complex • precatalytic spliceosome • nucleus • U2 snRNP • nucleoplasm Biological process • mRNA splicing, via spliceosome • mRNA processing • blastocyst formation • RNA splicing Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	51639	66055
Ensembl	ENSG00000115128	ENSMUSG00000037361
UniProt	Q9Y3B4	P59708
RefSeq (mRNA)	NM_016047	NM_025323
RefSeq (protein)	NP_057131	NP_079599.1 NP_079599
Location (UCSC)	Chr 2: 24.07 – 24.08 Mb	Chr 12: 4.82 – 4.83 Mb
PubMed search

2F9D, 2F9J, 2FHO, 3LQV

51639

66055

ENSG00000115128

ENSMUSG00000037361

Q9Y3B4

P59708

NM_016047

NM_025323

NP_057131

NP_079599.1
NP_079599

Splicing factor 3B, 14 kDa subunit, also known as SF3B14, is a human gene.

This gene encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site.

SF3B14 has been shown to interact with SF3B1.

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Wikipedia