SIL1

SIL1
Identifiers
Aliases	SIL1, BAP, MSS, ULG5, SIL1 nucleotide exchange factor
External IDs	MGI: 1932040 HomoloGene: 32544 GeneCards: SIL1
Gene ontology Molecular function • unfolded protein binding • protein binding Cellular component • endoplasmic reticulum lumen • endoplasmic reticulum • extracellular space Biological process • protein folding • protein transport • transport • intracellular protein transport Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	64374	81500
Ensembl	ENSG00000120725	ENSMUSG00000024357
UniProt	Q9H173	Q9EPK6
RefSeq (mRNA)	NM_001037633 NM_022464	NM_030749
RefSeq (protein)	NP_001032722 NP_071909	NP_109674.2 NP_109674
Location (UCSC)	Chr 5: 138.95 – 139.29 Mb	Chr 18: 35.27 – 35.5 Mb
PubMed search

64374

81500

ENSG00000120725

ENSMUSG00000024357

Q9H173

Q9EPK6

NM_001037633
NM_022464

NM_030749

NP_001032722
NP_071909

NP_109674.2
NP_109674

Nucleotide exchange factor SIL1 is a protein that in humans is encoded by the SIL1 gene.

This gene encodes a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome. Alternate transcriptional splice variants have been characterized.

SIL1 has been shown to interact with Binding immunoglobulin protein.

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Wikipedia