SLC45A2

SLC45A2
Identifiers
Aliases	SLC45A2, 1A1, AIM1, MATP, OCA4, SHEP5, solute carrier family 45 member 2
External IDs	MGI: 2153040 HomoloGene: 9412 GeneCards: SLC45A2
Gene ontology Molecular function • sucrose:proton symporter activity Cellular component • melanosome membrane • integral component of membrane • membrane Biological process • sucrose transport • developmental pigmentation • melanin biosynthetic process • response to stimulus • visual perception Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	51151	22293
Ensembl	n/a	ENSMUSG00000022243
UniProt	Q9UMX9	P58355
RefSeq (mRNA)	NM_001012509 NM_001297417 NM_016180	NM_053077
RefSeq (protein)	NP_001012527 NP_001284346 NP_057264	NP_444307.1 NP_444307
Location (UCSC)	Chr 5: 33.94 – 33.98 Mb	Chr 15: 11 – 11.03 Mb
PubMed search

51151

22293

n/a

ENSMUSG00000022243

Q9UMX9

P58355

NM_001012509
NM_001297417
NM_016180

NM_053077

NP_001012527
NP_001284346
NP_057264

NP_444307.1
NP_444307

Membrane-associated transporter protein (MATP) also known as solute carrier family 45 member 2 (SLC45A2) or melanoma antigen AIM1 is a protein that in humans is encoded by the SLC45A2 gene.

SLC45A2 is a transporter protein that mediates melanin synthesis. SLC45A2 is also a melanocyte differentiation antigen that is expressed in a high percentage of melanoma cell lines. A similar sequence gene in medaka, 'B,' encodes a transporter that mediates melanin synthesis. Mutations in this gene are a cause of oculocutaneous albinism type 4. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Wikipedia