SOD2

SOD2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1AP5, 1AP6, 1EM1, 1JA8, 1LUV, 1LUW, 1MSD, 1N0J, 1N0N, 1PL4, 1PM9, 1QNM, 1SZX, 1VAR, 1XDC, 1XIL, 1ZSP, 1ZTE, 1ZUQ, 2ADP, 2ADQ, 2GDS, 2P4K, 2QKA, 2QKC, 3C3S, 3C3T
Identifiers
Aliases	SOD2, IPOB, MNSOD, MVCD6, IPO-B, Mn-SOD, superoxide dismutase 2, mitochondrial
External IDs	OMIM: 147460 MGI: 98352 HomoloGene: 530 GeneCards: SOD2
Gene ontology Molecular function • superoxide dismutase activity • manganese ion binding • metal ion binding • identical protein binding • oxidoreductase activity Cellular component • mitochondrial matrix • mitochondrion • extracellular exosome Biological process • negative regulation of neuron apoptotic process • response to superoxide • response to reactive oxygen species • regulation of transcription from RNA polymerase II promoter • removal of superoxide radicals • vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure • regulation of blood pressure • age-dependent response to reactive oxygen species • negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway • protein homotetramerization • oxidation-reduction process • oxygen homeostasis • release of cytochrome c from mitochondria • superoxide metabolic process • negative regulation of cell proliferation Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	6648	20656
Ensembl	ENSG00000112096	ENSMUSG00000006818
UniProt	P04179	P09671
RefSeq (mRNA)	NM_000636 NM_001024465 NM_001024466 NM_001322814 NM_001322815 NM_001322816 NM_001322817 NM_001322819 NM_001322820	NM_013671
RefSeq (protein)	NP_000627 NP_001019636 NP_001019637 NP_001309743 NP_001309744 NP_001309745 NP_001309746 NP_001309748 NP_001309749	NP_038699.2 NP_038699
Location (UCSC)	Chr 6: 159.67 – 159.76 Mb	Chr 17: 13.01 – 13.02 Mb
PubMed search

1AP5, 1AP6, 1EM1, 1JA8, 1LUV, 1LUW, 1MSD, 1N0J, 1N0N, 1PL4, 1PM9, 1QNM, 1SZX, 1VAR, 1XDC, 1XIL, 1ZSP, 1ZTE, 1ZUQ, 2ADP, 2ADQ, 2GDS, 2P4K, 2QKA, 2QKC, 3C3S, 3C3T

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