SPEG

SPEG
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1U2H
Identifiers
Aliases	SPEG, APEG-1, APEG1, BPEG, SPEGalpha, SPEGbeta, CNM5, SPEG complex locus
External IDs	MGI: 109282 HomoloGene: 55619 GeneCards: SPEG
Gene location (Human) Chr. Chromosome 2 (human) Band 2q35 Start 219,434,846 bp End 219,498,287 bp
Gene location (Mouse) Chr. Chromosome 1 (mouse) Band 1 C4|1 38.88 cM Start 75,375,297 bp End 75,432,320 bp
Gene ontology Molecular function • transferase activity • nucleotide binding • protein serine/threonine kinase activity • protein kinase activity • protein binding • ATP binding • kinase activity Cellular component • cell nucleus Biological process • protein phosphorylation • muscle cell differentiation • muscle organ development • cell differentiation • phosphorylation • negative regulation of cell proliferation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	10290	11790
Ensembl	ENSG00000072195	ENSMUSG00000026207
UniProt	Q15772	Q62407
RefSeq (mRNA)	NM_001173476 NM_005876	NM_001085370 NM_001085371 NM_001173477 NM_007463
RefSeq (protein)	NP_001166947 NP_005867	NP_001078839 NP_001078840 NP_001166948 NP_031489
Location (UCSC)	Chr 2: 219.43 – 219.5 Mb	Chr 1: 75.38 – 75.43 Mb
PubMed search

1U2H

10290

11790

ENSG00000072195

ENSMUSG00000026207

Q15772

Q62407

NM_001173476
NM_005876

NM_001085370
NM_001085371
NM_001173477
NM_007463

NP_001166947
NP_005867

NP_001078839
NP_001078840
NP_001166948
NP_031489

SPEG complex locus, also known as SPEG, is a human gene.

Expression of this gene is thought to serve as a marker for differentiated vascular smooth muscle cells which may have a role in regulating growth and differentiation of this cell type. The encoded protein is highly similar to the corresponding rat and mouse proteins. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of only one variant has been defined.

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