STAG1

STAG1
Identifiers
Aliases	STAG1, SA1, SCC3A, stromal antigen 1
External IDs	MGI: 1098658 HomoloGene: 21191 GeneCards: STAG1
Gene location (Human) Chr. Chromosome 3 (human) Band No data available Start 136,336,233 bp End 136,752,403 bp
Gene location (Mouse) Chr. Chromosome 9 (mouse) Band No data available Start 100,597,798 bp End 100,959,375 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding • chromatin binding • protein binding Cellular component • chromosome • cytosol • chromatin • chromosome, centromeric region • nucleus • nucleoplasm • nuclear body • cohesin complex • nuclear matrix • mitotic spindle pole Biological process • chromosome segregation • cell division • cell cycle • transcription from RNA polymerase II promoter • positive regulation of transcription from RNA polymerase II promoter • sister chromatid cohesion • regulation of mitotic spindle assembly Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	10274	20842
Ensembl	ENSG00000118007	ENSMUSG00000037286
UniProt	Q8WVM7	Q9D3E6
RefSeq (mRNA)	NM_005862	NM_009282
RefSeq (protein)	NP_005853	NP_033308
Location (UCSC)	Chr 3: 136.34 – 136.75 Mb	Chr 3: 100.6 – 100.96 Mb
PubMed search

10274

20842

ENSG00000118007

ENSMUSG00000037286

Q8WVM7

Q9D3E6

NM_005862

NM_009282

NP_005853

NP_033308

Cohesin subunit SA-1 is a protein that in humans is encoded by the STAG1 gene.

This gene is a member of the SCC3 family and is expressed in the nucleus. It encodes a component of cohesin, a multisubunit protein complex that provides sister chromatid cohesion along the length of a chromosome from DNA replication through prophase and prometaphase, after which it is dissociated in preparation for segregation during anaphase.

STAG1 has been shown to interact with STAG2.

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Wikipedia