"Save You" is the third and last single from Simple Plan's self titled album. It was announced as the third single in a message to "SP Crew", the band's official members-only club.

Lead singer Pierre Bouvier has stated in interviews that the song deals with his brother's battle with cancer.

The song is in common time throughout and follows the basic ABABCB skeleton, with 'A' being the verse, 'B' being the prechorus and chorus, and 'C' being the bridge.

The song's verses are in the key of C natural minor and feature a i-VI-III-VII progression repeated three times, with a chord change every two beats. The song then enters a prechorus that slows into a half time. Background "Ohs" are heard as a slow B♭-A♭-B♭ progression is played. Using the B♭ (V/I), the song then modulates into E♭ major for the chorus which features a I-V-IV-V progression with a chord change every measure. This progression is repeated twice. The bridge is also in the key of C natural minor, but features a progression of i-VII-VI-VII. With a chord change every two beats. This progression is repeated six times. In the last three repeats, lead guitarist Jeff Stinco plays a short guitar interlude. The song ends in E♭ major on the dominant chord.

The music video was shot in late September 2008.[2]

The video premiered Friday October 24, 2008. It shows the band members performing in an open space, and then cancer survivors are shown lying on the floor, gradually they rise, and at the end of the video, their names appear. The video features band members' relatives who have survived cancer, and other cancer survivors such as Kevin Hearn, Sharon Osbourne, Marissa Jaret Winokur, René Angélil, Delta Goodrem, Anaheim Ducks alternate captain Saku Koivu and Bif Naked.

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