| Serena, Illinois | |
| Unincorporated community | |
| Country | United States |
|---|---|
| State | Illinois |
| County | LaSalle |
| Township | Serena |
| Elevation | 633 ft (193 m) |
| Coordinates | 41°29′10″N 88°43′53″W / 41.48611°N 88.73139°WCoordinates: 41°29′10″N 88°43′53″W / 41.48611°N 88.73139°W |
| Population | 980 (2000) |
| Government type | Township |
| Timezone | CST (UTC-6) |
| - summer (DST) | CDT (UTC-5) |
| ZIP code | 60549 |
| Area codes | 815, 779 |
Serena is an unincorporated community in LaSalle County, Illinois, United States. Serena has a post office with ZIP code 60549.