Shackleford is an unincorporated community in Saline County, in the U.S. state of Missouri.
Shackleford was laid out in 1879 when the railroad was extended to that point. A post office called Shackleford was established in 1879, and remained in operation until 1959. The community has the name of Thomas Shackleford, a railroad official.
Coordinates: 39°06′45″N 93°17′49″W / 39.11250°N 93.29694°W