Sir Eustace Edward Twisleton-Wykeham-Fiennes, 1st Baronet (29 February 1864 – 9 February 1943), known as Sir Eustace Fiennes, was a British soldier, Liberal politician and colonial administrator.
Fiennes was born in Reading, Berkshire, the second son of John Twisleton-Wykeham-Fiennes, 17th Baron Saye and Sele and his wife, Lady Augusta Hay-Drummond, a daughter of the 11th Earl of Kinnoull. He was educated at Malvern College,
In 1894, Fiennes married Florence Agnes Fletcher née Rathfelder (from Constantia, Cape Town). They lived in Windlesham and Sunningdale and had two children: John Eustace (1895–1917, Battle of Arras) and Sir Ranulph Twisleton-Wykeham-Fiennes, 2nd Baronet (1902–1943).
Fiennes fought in the North-West Rebellion in 1885, was stationed in Egypt from 1888–89, and took part in the expedition to Mashonaland in 1890. He was commissioned into the Queen's Own Oxfordshire Hussars in 1895, and promoted Lieutenant on 29 April 1899. Following the outbreak of the Second Boer War in late 1899, Fiennes volunteered for service in South Africa, and was commissioned as a lieutenant in the Imperial Yeomanry on 3 February 1900, serving in the 40th (Oxfordshire) company of the 10th Battalion. He left London the same day on board the SS Montfort. He was promoted Captain in 1901, Major in 1905, and Lieutenant-Colonel in 1918. He fought in Flanders and the Dardanelles during World War I.