| Spiridon Brusina | |
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1898 portrait of Spiridon Brusina
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| Born | December 11, 1845 |
| Died | May 21, 1909 (aged 63) |
| Nationality | Croatia |
| Fields | malacology |
Spiridon Brusina (11 December 1845 – 21 May 1909) was a Croatian malacologist.
Together with Oton Kučera and Gjuro Pilar, he founded the Croatian Society of Natural Sciences in Zagreb in the late 1885.