Stephania tetrandra
| Stephania tetandra | |
|---|---|
| Scientific classification | |
| Kingdom: | Plantae |
| (unranked): | Angiosperms |
| (unranked): | Eudicots |
| Order: | Ranunculales |
| Family: | Menispermaceae |
| Genus: | Stephania |
| Species: | S. tetrandra |
| Binomial name | |
|
Stephania tetrandra S. Moore |
|
Stephania tetrandra is a herbaceous perennial vine of the Menispermaceae family native to China and Taiwan. It grows from a short, woody caudex, climbing to a height of around three meters. The leaves are arranged spirally on the stem, and are peltate, i.e. with the leaf petiole attached near the centre of the leaf. Its root is used in traditional Chinese medicine (TCM).
Stephania tetrandra occurs in shrublands at village margins, open fields, and roadsides in South Central and East China in Anhui, Fujian, Guangdong, Guangxi, Hainan, Hubei, Hunan, Jiangxi, and Zhejiang provinces, and in Taiwan.
Stephania tetrandra is among the 50 fundamental herbs used in TCM. The standard pinyin according to the Chinese [Herbal] Pharmacopia of the People's Republic of China (Chinese: 中华人民共和国药典; pinyin: Zhonghua Renmin Gongheguo Yao Dian) is: fen fang ji (Chinese: 粉防己; pinyin: fěn fáng jǐ), but it is more commonly known as Han Fang ji (Chinese: 漢防己; pinyin: hàn fáng jǐ).
Fen fang ji is used in traditional Chinese medicine to dispel wind and dampness to relieve pain and to promote diuresis. It is classified as acrid, bitter and cold. The part used is the root.
Stephania contains tetrandrine, a potent smooth muscle relaxant.Stephania alkaloids have curare-like action, and can selectively inhibit T-cell-dependent immune reactions. The root contains many isoquinoline alkaloids: tetrandrine (0.6-0.9%), fangchinoline (0.5%), cyclanoline (0.1%) and dimethyltetrandrine iodide (muscle relaxant). The root also contains flavanoids. The main active alkaloids are: tetrandrine (12 to 23 grams/kg) and fangchinoline (0.3–3 mg/kg). Also present are: dimethyltetradine iodide, cyclanoline, menisine, menisidine, oxofangchirine, stephenanthrine, stepholidine and bisbenzylisoquinoline.
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Wikipedia