Sulfadimethoxine

Sulfadimethoxine

Clinical data
AHFS/Drugs.com	FDA Professional Drug Information
ATC code	J01ED02 (WHO) QJ01EQ09 (WHO) QP51AG02 (WHO)
Identifiers
IUPAC name 4-Amino-N-(2,6-dimethoxypyrimidin-4-yl)benzenesulfonamide
CAS Number	122-11-2 Y
PubChem CID	5323
DrugBank	DB06150 Y
ChemSpider	5132 Y
UNII	30CPC5LDEX
KEGG	D01142 Y
ChEBI	CHEBI:32161 Y
ChEMBL	CHEMBL62193 Y
ECHA InfoCard	100.004.113
Chemical and physical data
Formula	C12H14N4O4S
Molar mass	310.33 g/mol
3D model (Jmol)	Interactive image
SMILES COc1cc(nc(n1)OC)NS(=O)(=O)c2ccc(cc2)N
InChI InChI=1S/C12H14N4O4S/c1-19-11-7-10(14-12(15-11)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16) Y Key:ZZORFUFYDOWNEF-UHFFFAOYSA-N Y

Sulfadimethoxine (trade name Di-Methox, Albon) is a sulfonamide, it is not antibiotic, like it is sometimes mistakenly presented, it is an antibacterial fully synthesized medication. Albon is produced by Pfizer Animal Health and is available as an oral suspension, tablet or bolus. It is used to treat many infections including treatment of respiratory, urinary tract, enteric, and soft tissue infections.[5] It is most frequently used in veterinary medicine. Sulfadimethoxine inhibits bacterial synthesis of folic acid (pteroylglutamic acid) from para-aminobenzoic acid. It is also commonly used for the treatment of coccidiosis in many species.

Sulfadimethoxine is approved in Russia for use in humans, including children, and has been successfully used there for more than 35 years. It is widely available in Russia as an over-the-counter drug manufactured by a number of Russian pharmaceutical companies.

Some side effects include:

Animals should be kept well hydrated to prevent the formation of sulfa crystals in the animal's urine.[6]

It can be used for:

It has been shown to be effective against streptococci, klebsiella, proteus, shigella, staphylococci, escherichia, and salmonella.