TAGLN
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| Aliases | TAGLN, SM22, SMCC, TAGLN1, WS3-10, transgelin | ||||||||||||||||
| External IDs | MGI: 106012 HomoloGene: 2398 GeneCards: TAGLN | ||||||||||||||||
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| Species | Human | Mouse | |||||||||||||||
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| Location (UCSC) | Chr 11: 117.2 – 117.2 Mb | Chr 9: 45.93 – 45.94 Mb | |||||||||||||||
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Transgelin is a protein that in humans is encoded by the TAGLN gene.
The protein encoded by this gene is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear. Two transcript variants encoding the same protein have been found for this gene.
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Wikipedia