TRIO (gene)

TRIO
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1NTY, 2NZ8
Identifiers
Aliases	TRIO, ARHGEF23, tgat, trio Rho guanine nucleotide exchange factor, MEBAS, MRD44
External IDs	MGI: 1927230 HomoloGene: 20847 GeneCards: TRIO
Gene ontology Molecular function • transferase activity • nucleotide binding • protein kinase activity • guanyl-nucleotide exchange factor activity • kinase activity • protein serine/threonine kinase activity • protein binding • enzyme binding • ATP binding • Rho guanyl-nucleotide exchange factor activity Cellular component • cytoplasm • cytosol Biological process • phosphorylation • protein phosphorylation • transmembrane receptor protein tyrosine phosphatase signaling pathway • positive regulation of apoptotic process • regulation of Rho protein signal transduction • regulation of small GTPase mediated signal transduction • positive regulation of GTPase activity Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	7204	223435
Ensembl	ENSG00000038382	ENSMUSG00000022263
UniProt	O75962	Q0KL02
RefSeq (mRNA)	NM_007118	NM_001081302
RefSeq (protein)	NP_009049	NP_001074771
Location (UCSC)	Chr 5: 14.14 – 14.53 Mb	Chr 15: 27.73 – 28.03 Mb
PubMed search

1NTY, 2NZ8

7204

223435

ENSG00000038382

ENSMUSG00000022263

O75962

Q0KL02

NM_007118

NM_001081302

NP_009049

NP_001074771

Triple functional domain protein is a protein that in humans is encoded by the TRIO gene.

TRIO (gene) has been shown to interact with Filamin and RHOA.

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Wikipedia