TXNIP

TXNIP

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
4GEI, 4GEJ, 4GFX, 4LL1, 4LL4, 4ROF, 4ROJ, 5CQ2, 5DF6, 5DWS, 5DZD

Identifiers

TXNIP, thioredoxin interacting protein, EST01027, HHCPA78, THIF, VDUP1, ARRDC6

External IDs

MGI: 1889549 HomoloGene: 38186 GeneCards: TXNIP

Gene ontology
Molecular function	• enzyme inhibitor activity • protein binding • ubiquitin protein ligase binding
Cellular component	• cytoplasm • cytosol • mitochondrial intermembrane space • nucleus
Biological process	• cellular response to tumor cell • response to estradiol • negative regulation of catalytic activity • regulation of transcription, DNA-templated • protein import into nucleus • response to progesterone • response to mechanical stimulus • negative regulation of transcription from RNA polymerase II promoter • response to glucose • response to oxidative stress • transcription, DNA-templated • keratinocyte differentiation • response to calcium ion • negative regulation of cell division • regulation of cell proliferation • positive regulation of apoptotic process • cell cycle • platelet-derived growth factor receptor signaling pathway • response to drug • response to hydrogen peroxide
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE TXNIP 201010 s at fs.png

PBB GE TXNIP 201008 s at fs.png

PBB GE TXNIP 201009 s at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


10628


56338


ENSG00000265972


ENSMUSG00000038393


Q9H3M7


Q8BG60

RefSeq (mRNA)


NM_006472 NM_001313972


NM_001009935 NM_023719

RefSeq (protein)


NP_001300901 NP_006463


NP_001009935 NP_076208

Location (UCSC)

Chr 1: 145.99 – 146 Mb

Chr 3: 96.56 – 96.56 Mb

PubMed search

4GEI, 4GEJ, 4GFX, 4LL1, 4LL4, 4ROF, 4ROJ, 5CQ2, 5DF6, 5DWS, 5DZD

ENSG00000265972

ENSMUSG00000038393

NM_006472
NM_001313972

NM_001009935
NM_023719

NP_001300901
NP_006463

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Wikipedia

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