TYRO3

TYRO3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1RHF
Identifiers
Aliases	TYRO3, BYK, Dtk, RSE, Sky, Tif, Etk-2, Rek, TYRO3 protein tyrosine kinase
External IDs	MGI: 104294 HomoloGene: 4585 GeneCards: TYRO3
Gene ontology Molecular function • transferase activity • nucleotide binding • protein kinase activity • signal transducer, downstream of receptor, with protein tyrosine kinase activity • virus receptor activity • kinase activity • phosphatidylinositol 3-kinase binding • protein binding • protein heterodimerization activity • ATP binding • protein tyrosine kinase activity • transmembrane receptor protein tyrosine kinase activity Cellular component • integral component of membrane • nuclear envelope • endoplasmic reticulum membrane • membrane • plasma membrane • integral component of plasma membrane • nucleus Biological process • vagina development • phosphorylation • negative regulation of lymphocyte activation • protein phosphorylation • viral entry into host cell • phosphatidylinositol 3-kinase signaling • protein autophosphorylation • viral process • signal transduction • natural killer cell differentiation • cell adhesion • negative regulation of innate immune response • spermatogenesis • platelet activation • forebrain cell migration • apoptotic cell clearance • substrate adhesion-dependent cell spreading • peptidyl-tyrosine phosphorylation • ovulation cycle • negative regulation of neuron apoptotic process • platelet aggregation • signal transduction by protein phosphorylation • neuron cellular homeostasis • protein kinase B signaling • negative regulation of toll-like receptor signaling pathway • secretion by cell • negative regulation of inflammatory response Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	7301	22174
Ensembl	ENSG00000092445	ENSMUSG00000027298
UniProt	Q06418	P55144
RefSeq (mRNA)	NM_006293 NM_001330264	NM_001290800 NM_019392
RefSeq (protein)	NP_001317193 NP_006284	NP_001277729.1 NP_062265.2 NP_001277729 NP_062265
Location (UCSC)	Chr 15: 41.56 – 41.58 Mb	Chr 2: 119.8 – 119.82 Mb
PubMed search

1RHF

7301

22174

ENSG00000092445

ENSMUSG00000027298

Q06418

P55144

NM_006293
NM_001330264

NM_001290800
NM_019392

NP_001317193
NP_006284

NP_001277729.1
NP_062265.2
NP_001277729
NP_062265

Tyrosine-protein kinase receptor TYRO3 is an enzyme that in humans is encoded by the TYRO3 gene.

TYRO3 has been shown to interact with:

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