| State Route 43 | ||||
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| Maintained by TDOT | ||||
| Length: | 56.79 mi (91.39 km) | |||
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| Location | ||||
| Counties: | Madison, Gibson, Weakley, Obion | |||
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State Route 43 is a south to north highway in Tennessee that is 56.79 miles (91.39 km) long. It begins in Madison County and ends in Obion County. State Route 43 is little-known by the general public by this designation as it is overlain by U.S. Route 45E for most of its length; the "43" designation is seen largely on mileposts. Two short sections of this route at Martin and South Fulton is fully signed.
Most of SR 43 is a four-lane divided highway, which either overlies or bypasses its original route. It begins at Three Way as a divided four-lane, overlain by US 45E, bypasses Medina, and goes through Milan as an undivided four-lane. SR 43 from its southern terminus to Milan is designated as a Strategic Highway Network connector route servicing the Milan Arsenal. North of Milan, it becomes divided again and bypasses Bradford, passes through Greenfield undivided, divides again and bypasses Sharon.