Topterone

Topterone

Clinical data
Synonyms	WIN-17665; 17α-propyltestosterone; 17β-hydroxy-17α-propylandrost-4-en-3-one
Routes of administration	Topical
Identifiers
IUPAC name (8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-17-propyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
CAS Number	60607-35-4
PubChem CID	9797605
ChemSpider	39526
UNII	77WPB17ZK1
ECHA InfoCard	100.056.638
Chemical and physical data
Formula	C22H34O2
Molar mass	330.50416 g/mol
3D model (JSmol)	Interactive image
SMILES CCCC1(CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C)O
InChI InChI=1S/C22H34O2/c1-4-10-22(24)13-9-19-17-6-5-15-14-16(23)7-11-20(15,2)18(17)8-12-21(19,22)3/h14,17-19,24H,4-13H2,1-3H3/t17-,18+,19+,20+,21+,22+/m1/s1 Key:LZSOOHLAZHOTHJ-GUCLMQHLSA-N

Topterone (INN, USAN) (developmental code name WIN-17665), also known as 17α-propyltestosterone or 17α-propylandrost-4-en-17β-ol-3-one, is a steroidal antiandrogen that was first reported in 1978 and was developed for topical administration but, due to poor effectiveness, was never marketed.